Identifying and cloning a gene from a wheat cultivar resistant to stripe rust could lead to new cultivars that recognize and resist disease, according to a study appearing in the March issue of Nature Genetics. Researchers from the King Abdullah University of Science and Technology (KAUST) in Saudi Arabia along with collaborators from South Africa, France and the United States worked with a wheat cultivar from South Africa called Kariega that has a resistance to stripe rust, one of three species of wheat rust. They identified and cloned a gene, Yr27, that confers stripe rust resistance. The gene was cloned to study its function and molecular mechanisms of resistance.